Gipps Street in Collingwood will be closed to traffic on Thursday and Friday for the removal of a tower crane.
Traffic, including bikes, will not have access to the section adjacent to 48 Gipps St where a tower crane will be disassembled and removed.
Detours will be in place via local streets to get riders through the area.
Depending on direction of travel riders will be able to use Cromwell, Rupert, Langridge, Wellington. Or Vere, Campbell, McCutcheon and Rupert.
Traffic management will be in place.